교원프로필

반창일 사진
교원에 대한 정보를 나타내는 표입니다.
성명 반창일
소속 시스템생명공학부
전화번호 279-2127
E-mail CIBAN@POSTECH.AC.KR
Homepage http://bsb.postech.ac.kr/

학력

  • 1993~1996 THE OHIO STATE UNIV. (졸업-생화학)
  • 1991~1992 THE OHIO STATE UNIV. (졸업-생물리학)
  • 1982~1984 서울대학교 (졸업-화학)
  • 1978~1982 부산대학교 (졸업-화학)

주요경력

  • 2000~2002 : SUNY at Buffalo
  • 1999~2002 : H.W.I
  • 1996~1999 : N.I.H
  • 1996~1996 : Ohio state University
  • 1987~1988 : 동화약품 연구소
  • 1984~1986 : 부산대 화학과

전문분야

  • STRUCTURAL GENOMICS
  • FUNCTIONAL GENOMICS
  • 단백질 발현 및 분리법 개발
  • BIOSENSOR 개발
  • 종양지표 검지법 개발

학술지

국제전문학술지

  • Proteomic analysis of extracellular vesicles derived from Propionibacterium acnes, PROTEOMICS - Clinical Applications, , 11, - (2017)
  • Enzyme-linked antibody aptamer assays based colorimetric detection of soluble fraction of activated leukocyte cell adhesion molecule, Sensors and Actuators B: Chemical, , 242, 529-534 (2017)
  • Highly sensitive amperometric detection of cardiac troponin I using sandwich aptamers and screen-printed carbon electrodes, Talanta, , 165, 442-448 (2017)
  • Overexpression of angiotensin II type 1 receptor in breast cancer cells induces epithelial-mesenchymal transition and promotes tumor growth and angiogenesis, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, , 1863, 1071-1081 (2016)
  • Aptamer-nanoparticle complexes as powerful diagnostic and therapeutic tools, EXPERIMENTAL AND MOLECULAR MEDICINE, , 48, - (2016)
  • Enhanced electrochemical sensing of leukemia cells using drug/lipid co-immobilized on the conducting polymer layer, BIOSENSORS & BIOELECTRONICS, , 86, 33-40 (2016)
  • Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition, SCIENTIFIC REPORTS, , 6, - (2016)
  • A highly sensitive and selective impedimetric aptasensor for interleukin-17 receptor A, BIOSENSORS & BIOELECTRONICS, , 81, 80-86 (2016)
  • Ultrasensitive electrochemical detection of engrailed-2 based on homeodomain-specific DNA probe recognition for the diagnosis of prostate cancer, Biosensors and Bioelectronics, , 66, 32-38 (2015)
  • Ultrasensitive electrochemical detection of engrailed-2 based on homeodomain-specific DNA probe recognition for the diagnosis of prostate cancer, BIOSENSORS & BIOELECTRONICS, , 66, 32-38 (2015)
  • Formation of lipid bilayer membrane in a poly(dimethylsiloxane) microchip integrated with a stacked polycarbonate membrane support and an on-site nanoinjector, BIOMICROFLUIDICS, , 9, - (2015)
  • Electrochemical Aptasensor of Cardiac Troponin I for the Early Diagnosis of Acute Myocardial Infarction, ANALYTICAL CHEMISTRY, , 87, 9869-9875 (2015)
  • Dual aptamer-functionalized silica nanoparticles for the highly sensitive detection of breast cancer, BIOSENSORS & BIOELECTRONICS, , 71, 129-136 (2015)
  • Structural insights into Escherichia coli polymyxin B resistance protein D with X-ray crystallography and small-angle X-ray scattering, BMC STRUCTURAL BIOLOGY, , 14, - (2014)
  • Cationic Surfactant-Based Colorimetric Detection of Plasmodium Lactate Dehydrogenase, a Biomarker for Malaria, Using the Specific DNA Aptamer, PLOS ONE, , 9, - (2014)
  • Ultra-effective photothermal therapy for prostate cancer cells using dual aptamer-modified gold nanostars, JOURNAL OF MATERIALS CHEMISTRY B, , 2, 4862-4867 (2014)
  • Probing Conformational Change of Intrinsically Disordered alpha-Synuclein to Helical Structures by Distinctive Regional Interactions with Lipid Membranes, ANALYTICAL CHEMISTRY, , 86, 1909-1916 (2014)
  • An approach toward SNP detection by modulating the fluorescence of DNA-templated silver nanoclusters, BIOSENSORS & BIOELECTRONICS, , 43, 419-424 (2013)
  • A colorimetric aptasensor for the diagnosis of malaria based on cationic polymers and gold nanoparticles, Analytical Biochemistry, , 439, 11-16 (2013)
  • Stromal Cell Derived Factor-1 (SDF-1) Targeting Reperfusion Reduces Myocardial Infarction in Isolated Rat Hearts, CARDIOVASCULAR THERAPEUTICS, , 30, 264-272 (2012)
  • Aptasensor for ampicillin using gold nanoparticle-based dual fluorescence-colorimetric methods, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, , 402, 1-9 (2012)
  • Detection of the strand exchange reaction using DNAzyme and Thermotoga maritima recombinase A, ANALYTICAL BIOCHEMISTRY, , 421, 313-320 (2012)
  • A coordination polymer nanobelt (CPNB)-based aptasensor for sulfadimethoxine, BIOSENSORS & BIOELECTRONICS, , 33, 113-119 (2012)
  • Aptamers and Their Biological Applications, Sensors, , 12, 612-631 (2012)
  • ATP Alters the Diffusion Mechanics of MutS on Mismatched DNA, STRUCTURE, , 20, 1264-1274 (2012)
  • Label-free detection of kanamycin based on the aptamer-functionalized conducting polymer/gold nanocomposite, BIOSENSORS & BIOELECTRONICS, , 36, 29-34 (2012)
  • Electrochemical Evaluation of Binding Affinity for Aptamer Selection Using the Microarray Chip, ELECTROANALYSIS, , 24, 1057-1064 (2012)
  • A highly sensitive aptasensor towards Plasmodium lactate dehydrogenase for the diagnosis of malaria, BIOSENSORS & BIOELECTRONICS, , 35, 291-296 (2012)
  • Characterization of Multi-Functional Properties and Conformational Analysis of MutS2 from Thermotoga maritima MSB8, PLOS ONE, , 7, 34529- (2012)
  • A turn-on two-photon fluorescent probe for ATP and ADP, CHEMICAL COMMUNICATIONS, , 48, 3206-3208 (2012)
  • Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA (+) and PSMA (−) prostate cancers, Biomaterials, , 32, 2124-2132 (2011)
  • Simple Screening Method for Double-strand DNA Binders Using Hairpin DNA-modified Magnetic Beads, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, , 32, 247-250 (2011)
  • MutS switches between two fundamentally distinct clamps during mismatch repair, NATURE STRUCTURAL & MOLECULAR BIOLOGY, , 18, 379-U174 (2011)
  • Gold nanoparticle-based colorimetric detection of kanamycin using a DNA aptamer, ANALYTICAL BIOCHEMISTRY, , 415, 175-181 (2011)
  • Stromal Cell Derived Factor-1 (SDF-1) Targeting Reperfusion Reduces Myocardial Infarction in Isolated Rat Hearts, Cardiovascular Therapeutics, , 00, 1-9 (2011)
  • Modulated nicking endonuclease function by the N-terminal extended region of the smr domain in human Bcl-3 binding protein, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, , 80, 327-332 (2011)
  • An amperometric chloramphenicol immunosensor based on cadmium sulfide nanoparticles modified-dendrimer bonded conducting polymer, BIOSENSORS & BIOELECTRONICS, , 25, 1781-1788 (2010)
  • Simultaneous electrochemical detection of both PSMA (+) and PSMA (-) prostate cancer cells using an RNA/peptide dual-aptamer probe, CHEMICAL COMMUNICATIONS, , 46, 5566-5568 (2010)
  • Single-Molecule Analysis Reveals the Kinetics and Physiological Relevance of MutL-ssDNA Binding, PLOS ONE, , 5, - (2010)
  • Crystal Structures of Substrate and Inhibitor Complexes of Ribose 5-Phosphate Isomerase A from Vibrio vulnificus YJ016, MOLECULES AND CELLS, , 27, 99-103 (2009)
  • Functional properties of the thermostable mutL from Thermotoga maritima, BMB REPORTS, , 42, 53-58 (2009)
  • Structural Insights of the Nucleotide-Dependent Conformational Changes of Thermotoga maritima MutL Using Small-Angle X-ray Scattering Analysis, JOURNAL OF BIOCHEMISTRY, , 145, 199-206 (2009)
  • ASYMMETRIC SHORTER-DUPLEX SIRNA STRUCTURES TRIGGER EFFICIENT GENE SILENCING WITH REDUCED NONSPECIFIC EFFECTS, MOLECULAR THERAPY, , 17, 725-732 (2009)
  • Recognition of Single Mismatched DNA Using MutS-Immobilized Carbon Nanotube Field Effect Transistor Devices, JOURNAL OF PHYSICAL CHEMISTRY B, , 113, 12164-12168 (2009)
  • Dual-target gene silencing by using long, synthetic siRNA duplexes without triggering antiviral responses", MOLECULES AND CELLS, , 27, 689-695 (2009)
  • Effect of E. coli MutL on the steady-state ATPase activity of MutS in the presence of short blocked end DNAs, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, , 385, 225-229 (2009)
  • Detection for folding of the thrombin binding aptamer using label-free electrochemical methods, BMB REPORTS, , 41, 126-131 (2008)
  • A simple and direct electrochemical detection of interferon-gamma using its RNA and DNA aptamers, BIOSENSORS & BIOELECTRONICS, , 23, 1819-1824 (2008)
  • Detection of mismatched DNAs via the binding affinity of MutS using a gold nanoparticle-based competitive colorimetric method, CHEMICAL COMMUNICATIONS, , , 4573-4575 (2008)
  • A simple fluorescent method for detecting mismatched DNAs using a MutS-fluorophore conjugate, BIOSENSORS & BIOELECTRONICS, , 22, 1376-1381 (2007)
  • Crystal structure of recombinant human stromal cell-derived factor-1 alpha, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, , 67, 1193-1197 (2007)
  • Steady-state ATPase activity of E-coli MutS modulated by its dissociation from heteroduplex DNA, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, , 364, 264-269 (2007)
  • DNA mismatch repair system - Classical and fresh roles, FEBS JOURNAL, , 273, 1609-1619 (2006)
  • Crystal structures of the two isomorphous A-DNA decamers d(GTACGCGTAC) and d(GGCCGCGGCC), BULLETIN OF THE KOREAN CHEMICAL SOCIETY, , 27, 568-572 (2006)
  • Electrochemical detection of mismatched DNA using a MutS probe, NUCLEIC ACIDS RESEARCH, , 34, - (2006)
  • Crystallization and preliminary X-ray analysis of native and selenomethionyl polymyxin resistance protein D from E-coli, MACROMOLECULAR RESEARCH, , 13, 549-552 (2005)
  • Detection of protein-DNA interaction with a DNA probe: distinction between single-strand and double-strand DNA-protein interaction, NUCLEIC ACIDS RESEARCH, , 32, - (2004)
  • Development of a new and simple method for the detection of histidine-tagged proteins, BIOSENSORS & BIOELECTRONICS, , 20, 857-863 (2004)

국내전문학술지

일반학술지

  • Highly sensitive and selective in vitro diagnostics based on DNA probes and aptamers, Biodesign, , 3, 33-40 (2015)
  • Aptamer and it's Biological application: Biosensor, 센서 과학과 기술, , 2, 15-20 (2012)
  • DNA MISMATCH REPAIR: FROM STRUCTURE TO MECHANISM., COLD SPRING HARBOR SYMPOSIUM ON BIOLOGICAL RESPONSES TO DNA DAMAGE, , 65, 225-232 (2001)

학술회의논문

  • Structural and functional insight of the human endonuclease small MutS-related protein, 2009 STRUCTURAL FESTIVAL 초록, 0, 0, - (2009)
  • Novel diagnosis method of prostate cancer via specific dual-aptamer using electrochemical impedance stectroscopy, 대한화학회 제 103회 학술 초록, 0, 0, - (2009)
  • In vitro selection of oligonucleotides to antibiotics using affinity chromatography, 대한화학회 제 103회 학술 초록, 0, 0, - (2009)
  • X-ray crystallography study of hBubR1 N-terminal TPR domain, 대한화학회 제 103회 학술 초록, 0, 0, - (2009)
  • Crystallixation and preliminary X-ray crystallographic study of human MANF, 대한화학회 제 103회 학술 초록, 0, 0, - (2009)
  • Crystallization and X-ray Crystallographic study of human MANF, The 5th International Symposium and the 22th Workshop on Innovative BioPhysio Sensor Technology, 0, 0, - (2008)
  • Detection of SNPs using MutS protein and its application to biosensors, The 5th International Symposium and the 22th Workshop on Innovative BioPhysio Sensor Technology, 0, 0, - (2008)
  • X-ray crystallographic Study of hBubR1 N-terminal TPR domain, The 5th International Symposium and the 22th Workshop on Innovative BioPhysio Sensor Technology, 0, 0, - (2008)
  • A Cell based PSMA detection using its RNA aptamer, The 5th International Symposium and the 22th Workshop on Innovative BioPhysio Sensor Technology, 0, 0, - (2008)
  • In vitro selection of oligonucleotides to Ampicillin using affinity chromatography, The 5th International Symposium and the 22th Workshop on Innovative BioPhysio Sensor Technology, 0, 0, - (2008)
  • A simple and direct electrochemical method for detection of interferon-g using the RNA and DNA aptamers, The Tenth World Congress on Biosensers, 0, 0, - (2008)
  • Steady-state ATPase activitise of MutS in the presence of both ends blocked DNAs, The 65rd KSBMB Annual Meeting in 2008, 0, 0, - (2008)
  • Gold nanoparticle-based colorimetric detection of mismatched DNA using MutS protein, The 65rd KSBMB Annual Meeting in 2008, 0, 0, - (2008)
  • A simple and direct electrochemical method for detection of interferon-g using its RNA and DNA aptamers, The 65rd KSBMB Annual Meeting in 2008, 0, 0, - (2008)
  • Expanded structural repertoires to construct multiple silencing siRNAs, The 65rd KSBMB Annual Meeting in 2008, 0, 0, - (2008)
  • Functional characterization of MutS2 from Thermothoga maritima MSB8, The 65rd KSBMB Annual Meeting in 2008, 0, 0, - (2008)
  • Low resolution solution structure of methyl-directed mismatch repair protein MutL from Thermotoga maritima, The 101th KCS national meeting in 2008, 0, 0, - (2008)
  • A simple and direct detection of mismatched DNA using MutS probes, 바이오센서의 개발과 이용에 관한 심포지움, 0, 0, - (2007)
  • A simple method for detecting mismatched DNA using a MutS-IAANS conjugate, 대한화학회, 0, 0, - (2005)
  • A novel method for detecting mismatched DNA using a MutS-fluorophore conjugate, 한국생화학분자생물학회, 0, 0, - (2005)
  • Detection of protein-DNA interaction with a DNA probe, 한국생화학분자생물학회, 0, 0, - (2005)
  • Electrochemical Detection of mismatched DNA using immobilized MutS, 대한화학회, 0, 0, - (2004)
  • Structure and character comparison MutH with its variants, 대한 화학회 제94회 학술발표회, 0, 0, - (2004)
  • Oligonucleotides with Complementary and Non-complementary Base Pairing and Their Ligand Complexes - Major and Minor Nucleotide Conformations., In Aspects of crystallography in molecular biology, 0, 0, 333-352 (1997)
  • “Oligonucleotides with Complementary and Non-complementary Base Pairing and Their Ligand Complexes - Major and Minor Nucleotide Conformations.” (Review)., In Aspects of crystallography in molecular biology. Eds. S. Parthasarathy and J. P. Glusker, 0, 0, 333-352 (1997)
  • Detection of protein-DNA interaction with a DNA probe; distinction between ss- and ds-DNA-protein interaction, The 56th Annual Meeting of the international Society of Electrochemistry, 0, 0, - (0000)
  • Crystallization and Preliminary X-ray analysis of polymyxin resistance protein D from E.coli, The 6th CIMS workshop, 0, 0, - (0000)
  • Crystallization of small mutant related protein, Ydal from E.coli, The 6th CIMS workshop, 0, 0, - (0000)
  • Detection of Mismatched DNA Using a MutS-Fluorophore Conjugate, The 6th CIMS workshop, 0, 0, - (0000)
  • Purification and crystallization of Ribose-5-Phosphate isomerase A (RpiA) From Vibrio Vulnificus, The 6th CIMS workshop, 0, 0, - (0000)
  • Purification and Preliminary X-ray crystallographic analysis of human SDF-1a, The 6th CIMS workshop, 0, 0, - (0000)
  • Structural Study on Human BubR1, a Mitotic Checkpoint Protein, The 6th CIMS workshop, 0, 0, - (0000)
  • Crystal Structures of the Two Isomorphous A-DNA Decamers d(GTACGCGTAC) and d(GGCCGCGGCC), 대한화학회, 0, 0, - (0000)
  • Study on electrochemical Aptamer Sensor for Thrombin Detection, 대한화학회, 0, 0, - (0000)
  • Crystal structure of refolded human stromal cell derived factor-1a, 63rd KSBMB Annual Meeting, 0, 0, - (0000)
  • Structural analysis of ribose-5-phosphate isomerase and its mutants, 63rd KSBMB Annual Meeting, 0, 0, - (0000)
  • Electrochemical detection of mismatched DNA using a MutS probe, th Annual Nucleic Acid-Based Technologies, 0, 0, - (0000)
  • A simple fluorescence method for detecting mismatched DNA using a MutS-fluorophore conjugate, The 3rd International Symposium and The 14th Workshop on Innovative Biophysio Sensor Technology, 0, 0, - (0000)
  • Highly sensitive an aptamer based IFN-r sensor for detection of a tuberculosis p, 제99회 대한화학회 춘계총회 및 학술발표회, 0, 0, - (0000)
  • Label-free electrochemical detection for folding of the thrombin binding aptamer, 제99회 대한화학회 춘계총회 및 학술발표회, 0, 0, - (0000)
  • Functional insight into thermostable mismatch repair proteins mutL from thermotoga maritima MSB8, 19th FAOBMB Seoul Conference, 0, 0, - (0000)
  • A simple fluorescence method for detecting mismatched DNA using a MutS-fluorophore conjugate, 8th International Conference Biodetection Technologies, 0, 0, - (0000)
  • Crystallization and Preliminary X-ray Crystallographic study of PmrD from E.coli, The 3rd International Symposium and The 14th Workshop on Innovative BiophysioSensor Technology, 0, 0, - (0000)
  • Detection for folding of the thrombin binding aptamer using label-free electrochemical methods, The 3rd International Symposium and The 14th Workshop on Innovative BiophysioSensor Technology, 0, 0, - (0000)
  • Highly sensitive aptamer based sensor for detection of IFN-r, The 3rd International Symposium and The 14th Workshop on Innovative BiophysioSensor Technology, 0, 0, - (0000)
  • Purification and crystallization of UspA from vibrio vulnificus, The 3rd International Symposium and The 14th Workshop on Innovative BiophysioSensor Technology, 0, 0, - (0000)
  • Study of expression, purification and crystallization of hBubR1, The 3rd International Symposium and The 14th Workshop on Innovative BiophysioSensor Technology, 0, 0, - (0000)
  • A simple fluorescence method for detecting mismatched DNA using a MutS-fluorophore conjugate, 8th International Conference Biodetection Technologies, 0, 0, - (0000)
  • Structural analysis of ribose-5-phosphate isomerase and its mutants in Vibrio Vulnificus, The 3rd International Symposium and The 14th Workshop on Innovative Biophysio Sensor Technology, 0, 0, - (0000)

학회발표

  • 단백질 바이오마커 검출을 위한 초고감도 압타머 기반 센서 개발, ., 0, 0, - (2017)
  • An electrochemical aptasensorof cardiac troponin I for the early diagnosis of acute myocardial infarction, ., 0, 0, - (2015)
  • Diagnosis of liver cancer based on ELLAA method utilizing aptamer, ., 0, 0, - (2015)
  • Ultra-sensitive Aptasensor for the Detection of Target Biomarker, ., 0, 0, - (2015)
  • Detection of ALCAM (CD166) based on aptamer-antibody sandwich ELISA method, ., 0, 0, - (2015)
  • N-terminal prohormone of brain natriuretic peptide (NT-proBNP) binding DNA aptamer for the diagnosis of acute myocardial infarction (AMI), ., 0, 0, - (2015)
  • The Effective Aptasensor for Detection of IL-2 sRA for Estimating Over-activation of Lymphocytes, ., 0, 0, - (2015)
  • Development of detection system using ssDNA aptamer to Tuberculosis Antigens CFP10 and TB7.7(Rv2654c), ., 0, 0, - (2015)
  • Ultra-effective photothermal therapy for prostate cancer cells using dual aptamer-modified gold nanostars, ., 0, 0, - (2014)
  • The Diagnosis of Malaria Using Colorimetric Aptasensor with Gold Nanoparticles., ., 0, 0, - (2014)
  • Cationic Surfactant-Based Colorimetric Detection of Plasmodium Lactate Dehydrogenase, a Biomarker for Malaria, Using the Specific DNA Aptamer, ., 0, 0, - (2014)
  • The diagnosis of malaria using colorimetric aptasensor with gold nanoparticles, ., 0, 0, - (2014)
  • Effective therapy for prostate cancers, ., 0, 0, - (2014)
  • The Diagnosis of Malaria Using Colorimetric Aptasensor with Gold Nanoparticles., ., 0, 0, - (2014)
  • Ultra-effective photothermal therapy for prostate cancer cells using dual aptamer-modified gold nanostars, ., 0, 0, - (2014)
  • Structural and Functional Study on yC1D/Rrp47:Overall Structure, Domain Location and dsDNA Interaction, ., 0, 0, - (2014)
  • Structural insights into Escherichia coli polymyxin B resistance protein D with X-ray crystallography and small-angle X-ray scattering, ., 0, 0, - (2014)
  • Aptamer-based detection of cardiac biomarker troponin I with high sensitivity, ., 0, 0, - (2014)
  • Aptamer-based colorimetric detection of plasmodium lactate dehydrogenase using cationic polymers for the diagnosis of malaria., ., 0, 0, - (2014)
  • Development of the aptasensor to detect cardiac biomarker Troponin I with high sensitivity and specificity, ., 0, 0, - (2014)
  • Colorimetric aptasensor towards Plasmodium lactate dehydrogenase for the rapid diagnosis of malaria, ., 0, 0, - (2013)
  • Aptasensor for cardiac biomarker Troponin I using Ferrocene (Fc) – modified silica nanoparticles, ., 0, 0, - (2013)
  • Ultra-efficient photothermal therapy for prostate cancers using aptamer-modified gold nanostars, ., 0, 0, - (2013)
  • Aptamer-based colorimetric detection of malaria biomarkers in vitro and in infected blood samples using gold nanoparticles and CTAB, ., 0, 0, - (2013)
  • Structural studies of E. coli PmrD using X-ray crystallography and SAXS, ., 0, 0, - (2013)
  • Structural studies of E. coli PmrD using X-ray crystallography and SAXS, ., 0, 0, - (2013)
  • Structural study of human creatine kinase using SAXS, ., 0, 0, - (2013)
  • Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA(+) and PSMA(–) prostate cancers, ., 0, 0, - (2013)
  • label-free electrochemical detection of cardiac biomarker troponin I for the diagnosis of acute myocardial infarction, ., 0, 0, - (2012)
  • monitoring of in vitro DNA recombination using impedimetry, ., 0, 0, - (2012)
  • development and characterization of ssDNA aptamers against plasmodium lactate dehydrogenase. a biomarker for malaria, ., 0, 0, - (2012)
  • Development of aptamers for sulfadimethoxine, ., 0, 0, - (2012)
  • development of biosensors using an aptamer probes, ., 0, 0, - (2012)
  • Dual-aptamer-based electrochemical detection of both PSMA(+) and PSMA(-) prostate cancer cells and delivery vehicle of doxorubicin to the cells, ., 0, 0, - (2012)
  • A coordination polymer nanobelt (CPNB)-based aptasensor for sulfadimethoxine, ., 0, 0, - (2012)
  • A novel and highly sensitive electrochemical aptasensor towards Plasmodium lactate dehydrogenase for the diagnosis of malaria, ., 0, 0, - (2012)
  • Aptasensor for ampicillin using gold nanoparticle-based dual fluorescence-colourimetric methods, ., 0, 0, - (2012)
  • Detection of the strand exchange reaction using DNAzyme and Thermotoga Maritima recombinase A, ., 0, 0, - (2012)
  • Gold nanoparticle-based colorimetric detection of kanamycin using a DNA aptamer, ., 0, 0, - (2012)
  • Label-free electrochemical detection of cardiac biomarker troponin I using single-stranded DNA aptamer, ., 0, 0, - (2012)
  • Structural and functional study of Thermotoga maritima MutS2 and Human Bcl-3 binding protein Smr domain, ., 0, 0, - (2011)
  • Development of Biosensors using an Aptamer Probe and a DNAzyme, ., 0, 0, - (2011)
  • Development of Biosensors using Aptamer Probes and a DNAzyme, ., 0, 0, - (2011)
  • Purification of GTPBP1 for the structural study on mRNA stability, ., 0, 0, - (2011)
  • Selective delivery of doxorubicin to prostate cancer cells using nanoparticles modified by aptamers, ., 0, 0, - (2011)
  • SAXS analysis and functional study of Thermotoga maritima MutS2, ., 0, 0, - (2011)
  • Study on the development of detection method using selected aptamer for ampicillin, ., 0, 0, - (2011)
  • The expression and purification of human NTH1 protein for functional and structural study, ., 0, 0, - (2011)
  • Structural analysis and functional study of the human small MutS-related protein, ., 0, 0, - (2010)
  • Study on the interaction between the Plasmodium vivax circumsporozoite protein and Human importin alpha 3, ., 0, 0, - (2010)
  • Magnetic bead-based method of screening double-strand DNA binders, ., 0, 0, - (2010)
  • Studies on the functional properties of recombinant SDF-1, ., 0, 0, - (2010)
  • Structural analysis and Functional study of Smr domain in Human B3bp, ., 0, 0, - (2010)
  • Purification of Importin alpha 3 for the studies on structure and function, ., 0, 0, - (2010)
  • Study on detection system for kanamycin using new aptamer by gold-nanoparticle colorimetry, ., 0, 0, - (2010)
  • Gold nanoparticle-based colorimetry assay using ssDNA aptamer specific for kanamycin, ., 0, 0, - (2010)
  • Structural Analysis and Functional Studies of Thermotoga maritima MutS2, ., 0, 0, - (2010)
  • Separation of hairpin DNA binding materials using magnetic separation, ., 0, 0, - (2010)
  • Therapeutic Approach of SDF-1 Related Diseases and Functional Study of Recombinant SDF-1, ., 0, 0, - (2010)
  • Expression and purification of Importin alpha 3 for X-ray crystallographic analysis, ., 0, 0, - (2010)
  • Plasmodium circumsporozoite protein directly interacts with the major porket of Human importin alpha 3, ., 0, 0, - (2010)
  • Simultaneous electrochemical detection of both PSMA (+) and PSMA (-) prostate cancers using RNA/peptide aptamer probe, ., 0, 0, - (2010)
  • Simultaneous electrochemical detection of both PSMA (+) and PSMA (-) prostate cancers using RNA/peptide aptamer probe, ., 0, 0, - (2010)
  • Electrochemical detection of mismatched DNA using a MutS probe, ., 0, 0, - (2010)
  • Synchronous targeting of doxorubicin to two types of prostate cancer cells using an RNA/peptide aptamer conjugate, ., 0, 0, - (2010)
  • Detection for folding of the thrombin binding aptamer using label-free electrochemical methods, ., 0, 0, - (2010)
  • Semi-Structural Genomics of DNA Repairing and Checkpoint Proteins for Damaged DNA, , 0, 0, - (0000)
  • Semi-Structural Genomics of DNA Repairing and Checkpoint Proteins:X-ray crystallography, , 0, 0, - (0000)
  • DNA-ATP-Protein Interactions in DNA Mismatch Repairing Proteins, MutS, MutL and MutH, , 0, 0, - (0000)
  • Functional Role of ATP in DNA Mismatch Repair, , 0, 0, - (0000)
  • Functional Role of Intermolecular Interactions in the Initiation of DNA repairing: Crystal Structure of MutL, , 0, 0, - (0000)
  • Crystal Structure of DNA Mismatch Repair Protein MutS and its Complex with a Substrate DNA, , 0, 0, - (0000)
  • Structural and Functional Genomics, , 0, 0, - (0000)
  • Semi-Structural Genomics of DNA Repairing and Checkpoint Proteins, , 0, 0, - (0000)
  • Development of Cancer Indicating Sensor Using Telomere and Telomerase, , 0, 0, - (0000)
  • Intermolecular Network and Biophysical Characterization of Checkpoint Proteins, , 0, 0, - (0000)
  • Cloning and expression of microbial lipases, The 3rd Symposium of CIBST, 0, 0, - (0000)
  • Electrochemical and structural studies of telomerase, The 3rd Symposium of CIBST, 0, 0, - (0000)
  • Electrochemical detection of mismatch DNA using immobilized MutS, The 3rd Symposium of CIBST, 0, 0, - (0000)
  • Structural and biochemical studies of human checkpoint 2 (hChk2) protein, The 3rd Symposium of CIBST, 0, 0, - (0000)
  • Structural and biophysical studies of E.coli MutL, The 3rd Symposium of CIBST, 0, 0, - (0000)
  • Structural study of taq MutS protein complex with mismatched DNA, The 3rd Symposium of CIBST, 0, 0, - (0000)
  • Electrochemical Detection of Mismatched DNA Using Immobilized MutS, The 6th CIMS symposium, 0, 0, - (0000)
  • Expression and purification of human DNA damage checkpoint Rad complexes (Rad9-Rad1-Hus1), The 6th CIMS symposium, 0, 0, - (0000)
  • Expression and purification of polymyxin resistance protein (pmrD), The 6th CIMS symposium, 0, 0, - (0000)
  • Structural and biophysical studies of e. coli MutL, The 6th CIMS symposium, 0, 0, - (0000)
  • Electrochemical Detection of mismatched DNA using immobilized MutS, 제61회 한국생화학분자생물학회, 0, 0, - (0000)
  • New Strategy of Structural and Functional Genomics, , 0, 0, - (0000)
  • 손상된 DNA 센서개발을 위한 단백질 고정화법에 관한 연구, The 1st International Symposium on Innovative Bio-Physio Sensor Technology, 0, 0, - (0000)
  • 암세포의 초기진단 센서개발을 위한 기초 연구, The 1st International Symposium on Innovative Bio-Physio Sensor Technology, 0, 0, - (0000)
  • Electrochemical detection of mismatch DNA using immobilized MutS, The 1st International Symposium on Innovative Bio-Physio Sensor Technology, 0, 0, - (0000)
  • SAW 전달면및 nano 입자 표면의 바이오 물질 고정화법 기초연구, The 1st International Symposium on Innovative Bio-Physio Sensor Technology, 0, 0, - (0000)
  • Electrochemical Detection of Mismatch DNA using Immobilized MutS, 대한 화학회 제94회 학술발표회, 0, 0, - (0000)
  • Helicase activity of UvrD is dependent on MutL and MutS, 대한 화학회 제94회 학술발표회, 0, 0, - (0000)
  • Structural Study on E. coli. PmrD, a PolymyxinB resistant Protein., The 5th Center for Integrated Molecular Systems Workshop, 0, 0, - (0000)
  • Structural Study on hKIP, a Kinase Interacting Protein., The 5th Center for Integrated Molecular Systems Workshop, 0, 0, - (0000)
  • Detection of protein-DNA interaction with a DNA probe: distinction between single-strand and double-strand DNA-protein interaction., The 62th 대한 생화학/분자생물학회 제62회 학술 발표회, 0, 0, - (0000)
  • Expression, Purification, and Characterization of Helicase UvrD in Helicobacter pylori., The 2nd International Syposium and The 10th Workshop on Innovative Biophysio Sensor Technology, 0, 0, - (0000)
  • Purification and crystallization of adenylyl cyclase and its complex with an inhibitor, bisdemethoxycurcumin., The 2nd International Syposium and The 10th Workshop on Innovative Biophysio Sensor Technology, 0, 0, - (0000)
  • Purification and crystallization of Ribose-5-Phosphate isomerase A (RpiA)., The 2nd International Syposium and The 10th Workshop on Innovative Biophysio Sensor Technology,, 0, 0, - (0000)
  • Structural study on Human-KIP, a kinase interacting protein., The 2nd International Syposium and The 10th Workshop on Innovative Biophysio Sensor Technology,, 0, 0, - (0000)
  • Crystallization and Preliminary X-ray Analysis of Native and Selenomethionyl Polymyxin Resistance Protein D from E. coli,, The 3rd International Symposium of X-ray and Neutron Scattering on Integrated Molecular Systems, 0, 0, - (0000)
  • A simple fluorescence method for detecting mismatched DNA using a MutS-fluorophore conjugate., The 5th Center for Integrated Molecular Systems Workshop, 0, 0, - (0000)
  • Development of Universal DNA Mismatch Sensor Using MutS, , 0, 0, - (0000)
  • DNA Mismatch Repair: From Structure to Mechanism, , 0, 0, - (0000)
  • Electrochemical Detection of Mismatched DNA Using Immobilized MutS, The 5th Center for Integrated Molecular Systems Workshop, 0, 0, - (0000)
  • Purification and crystallization of adenylyl cyclase and its complex with an inhibitor, bisdemethoxycurcumin., The 5th Center for Integrated Molecular Systems Workshop, 0, 0, - (0000)
  • Semi-Structural Genomics of DNA Repairing and Checkpoint Proteins: X-ray crystallography, , 0, 0, - (0000)
  • Temperature induced folding study of a-synuclein, The 3rd Symposium of CIBST, 0, 0, - (0000)
  • Detection of protein-DNA interaction with a DNA probe: distinction between single-strand and double-strand DNA-protein interaction., The 56th Annual Meeting of the International Society of Electrochemistry, 0, 0, - (0000)
  • A simple fluorescence method for detecting mismatched DNA using a MutS-fluorophore conjugate., 8th International Conference Biodetection Technologies 2006, 0, 0, - (0000)
  • Structural analysis of ribose-5-phosphate isomerase and its mutants in Vibrio Vulnificus, The 3rd International Symposium and The 14th Workshop on Innovative Biophysio Sensor Technology, 0, 0, - (0000)
  • The role of HIF-1a in nucleic acid-triggered antiviral innate immune responses, The 65rd KSBMB Annual Meeting in 2008, 0, 0, - (0000)

단행본

연구실적

  • 인체 CHECKPOINT 단백질들의 구조 및 생화학적 특성화에 관한 연구, 포항공과대학교 (2002-2003)
  • 암에 관련된 단백질들의 삼차원 구조와 기능의 규명, 그리고 항암제 개발로의 응용에 관한 연, 포항공과대학교 (2003-2004)
  • DNA수복 초기 단계에서의 단백질 -DNA 상호작용의 기작 규명을 위한 생분석 화학 및, 한국학술진흥재단 (2004-2005)
  • 암에 관련된 단백질들의 삼차원 구조와 기능의 규명, 그리고 하암제 개발로의 응용에 관한 연, 포항공과대학교 (2005-2005)
  • 농산물에 첨가된 항생제의 APTAMER 라이브러리 구축, 부산대학교산학협력단 (2007-2008)
  • 농산물에 첨가된 항생제의 APTAMER 라이브러리 구축, 부산대학교산학협력단 (2008-2009)
  • 잘못된 염기 수복 DNA 반응기작에 관여하는 단백질들의 구조 및 기능적 연구, 한국학술진흥재단 (2008-2009)
  • 인건비풀링과제, 포항공과대학교 (2009-2015)
  • 자체연구개발과제, 포항공과대학교 (2009-2016)
  • 이종 압타머 시스템을 이용한 전립선암에 대한 능동적 약물전달 및 조영제로서의 응용, (재)한국과학창의재단 (2009-2009)
  • 잘못된 염기 수복 DNA 반응기작에 관여하는 단백질들의 구조 및 기능적 연구, 한국학술진흥재단 (2009-2010)
  • 농.축산품중 잔류 항생제 인식 APTAMER 개발, 부산대학교산학협력단 (2009-2010)
  • 학생인건비 풀링과제(국가기관), 포항공대산학협력단 (2009-2020)
  • 4.3036 1차년도 이월과, 한국학술진흥재단 (2009-2010)
  • DNAZYME을 이용한 비가역적 재조합 센서에 관한 연구(학부생연구프로그램), 포항공과대학교 (2009-2010)
  • 잘못된 염기 수복 DNA 반응기작에 관여하는 단백질들의 구조 및 기능적 연구, 재단법인한국연구재단 (2010-2011)
  • 질병 및 암 진단을 위한 SMALL NON-CODING RNA 신물질 발굴 및 진단용 검출 시스템 개발, 재단법인한국연구재단 (2011-2012)
  • 질병 및 암 진단을 위한 SMALL NON-CODING RNA 신물질 발굴 및 진단용 검출 시스템 개발, 재단법인한국연구재단 (2012-2013)
  • 표적 압타머-약물전달체 이용 유방암 표적치료제 개발, 고려대학교산학협력단 (2012-2013)
  • 질병 및 암 진단을 위한 SMALL NON-CODING RNA 신물질 발굴 및 진단용 검출 시스템 개발, 재단법인한국연구재단 (2013-2014)
  • (이창민-화학)DUAL-APTAMER를 이용한 PSMA(+)와 PSMA(-) 전립선암의 광열치료법 개발, 포항공과대학교 (2013-2013)
  • (윤형준-화학)압타머와 산화 그래핀을 이용한 항생제 다중 검출법 개발, 포항공과대학교 (2013-2013)
  • 심근경색 치료를 위한 차세대 표적지향 압타머 전달체의 개발, 경희대학교산학협력단 (2013-2014)
  • 차세대 바이오마커와 압타머를 이용한 전립선암의 진단 및 예후 기술 개발, 재단법인한국연구재단 (2013-2014)
  • 압타머를 활용한 유방암 진단 및 치료법 개발, (재)한국과학창의재단 (2013-2014)
  • 압타머 발굴과 유방암 진단 및 치료제 개발, 고려대학교산학협력단 (2013-2014)
  • (IBS)복잡계 자기조립 연구단 학과 지원금, 포항공과대학교 (2013-2017)
  • 차세대 바이오마커와 압타머를 이용한 전립선암의 진단 및 예후 기술 개발, 재단법인한국연구재단 (2014-2015)
  • 심근경색 치료를 위한 차세대 표적지향 압타머 전달체의 개발, 경희대학교산학협력단 (2014-2015)
  • 표적 압타머-약물전달체 이용 유방암 표적치료제개발, 고려대학교산학협력단 (2014-2015)
  • 기술료 연구개발재투자과제, 포항공대산학협력단 (2015-2016)
  • 화학과 기술료수입 배분과제, 포항공과대학교 (2015-2016)
  • 차세대 바이오마커와 압타머를 이용한 전립선암의 진단 및 예후 기술 개발, 재단법인한국연구재단 (2015-2016)
  • 2015_IBS유치기관지원금(학과지원비)-복잡계자기조립연구단, 포항공과대학교 (2015-2017)
  • 자체연구개발과제[2015년 신설], 포항공과대학교 (2015-2024)
  • 4.11098_1단계 2차년도 이월과제, 재단법인한국연구재단 (2015-2016)
  • 압타머 발굴과 유방암 진단 및 치료제 개발, 고려대학교산학협력단 (2015-2016)
  • 결핵 특이 단백질 정량 압타머센서 개발, 한국보건산업진흥원 (2015-2016)
  • 펩타이드리간드-고분자 CONJUGATE 합성, (주)삼양바이오팜 의약연구소 (2016-2016)
  • 2016년_IBS 유치기관 지원금(학과지원비), 포항공과대학교 (2016-2017)
  • 허준석_무은재펠로우십 학과매칭, 포항공과대학교 (2016-2017)
  • 허준석_무은재펠로우십 대학매칭, 포항공과대학교 (2016-2017)
  • 압타머 발굴과 유방암 진단 및 치료제 개발, 고려대학교산학협력단 (2016-2017)
  • 결핵 특이 단백질 정량 압타머센서 개발, 부산대학교산학협력단 (2016-2017)
  • [화학]지식재산출원등록비 연구자별 과제, 포항공대산학협력단 (2017-2029)
  • 2017_IBS(복잡계자기조립연구단)학과지원금, 포항공과대학교 (2017-2017)

IP

  • 반창일,김윤근,전진성, 프로피오니박테리움 아크네스 유래 나노소포 및 이의 용도, 한국, 10-2017-0081782 (2017)
  • 김윤근,반창일,전진성, 프로피오니박테리움 속 세균 유래 나노소포 및 이의 용도, -, PCT/KR2017/0068 (2017)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 중국, 201710085018.X (2016)
  • 반창일,전진성,김윤근, 프로피오니박테리움 아크네스 유래 나노소포 및 이의 용도, 한국, 10-2016-0087058 (2016)
  • 반창일,김윤근,이성환,조헌호,윤형준, EN2에 특이적으로 결합하는 DNA 압타머 및 이의 용도, USA, 10-2014-0188124 (2015)
  • 반창일,김윤근,이성환,조헌호,윤형준, EN2에 특이적으로 결합하는 DNA 압타머 및 이의 용도, USA, 14/933,113 (2015)
  • 반창일,김윤근,이성환,조헌호,윤형준, EN2에 특이적으로 결합하는 DNA 압타머 및 이의 용도, USA, 14/933,113 (2015)
  • 김윤근,반창일,조헌호,이성환,윤형준, EN2에 특이적으로 결합하는 DNA 압타머 및 이의 용도, 일본, 2015-094438 (2015)
  • 반창일,김윤근,조헌호,이성환,윤형준, EN2에 특이적으로 결합하는 DNA 압타머 및 이의 용도, 일본, 2015-094438 (2015)
  • 반창일,이성환,전위정, pLDH에 특이적으로 결합하는 DNA 압타머, 독일, 12151425.1 (2015)
  • 반창일,이성환,전위정, pLDH에 특이적으로 결합하는 DNA 압타머, 독일, 12151425.1 (2015)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 영국, 12151421.0 (2014)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 영국, 12151421.0 (2014)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 독일, 12151421.0 (2014)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 독일, 12151421.0 (2014)
  • 반창일,조헌호,윤형준,이성환,김윤근, EN2에 특이적으로 결합하는 DNA 압타머 및 이의 용도, 한국, 10-2014-0188124 (2014)
  • 반창일,조헌호,윤형준,이성환,김윤근, EN2에 특이적으로 결합하는 DNA 압타머 및 이의 용도, 한국, 10-2014-0188124 (2014)
  • 반창일,조헌호,서재홍,김지영, HER-2 표적화 압타머 복합체 및 이의 용도, 한국, 10-2014-0123869 (2014)
  • 반창일,조헌호,서재홍,김지영, HER-2 표적화 압타머 복합체 및 이의 용도, 한국, 10-2014-0123869 (2014)
  • 반창일,전위정,송경미, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 한국, 10-2011-0145434 (2011)
  • 반창일,전위정,송경미, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 한국, 10-2011-0145434 (2011)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 중국, 미접수 (2011)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 중국, 201210015204.3 (2011)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 일본, 2012-009785 (2011)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, 일본, 2012-009785 (2011)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, USA, 13/355,234 (2011)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, USA, 13/355,234 (2011)
  • 반창일,송경미,전위정, 인간 심근 트로포닌 Ⅰ에 특이적으로 결합하는 DNA 압타머, EP, 12151421.0 (2011)
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