교원프로필

Surh Charles D. 사진
교원에 대한 정보를 나타내는 표입니다.
성명 Surh Charles D.
소속 융합생명공학부
전화번호 279-0650
E-mail CSURH@POSTECH.AC.KR
Homepage http://tcb.postech.ac.kr/

학력

  • 1984~1989 UNIV. OF CALIFORNIA AT DAVIS (졸업-Immunology)
  • 1978~1983 UNIV. OF CALIFORNIA AT SAN DIEGO (졸업-chemistry)

주요경력

  • 2008~2012 : THE SCRIPPS RESEARCH INSTITUTE
  • 2005~2008 : THE SCRIPPS RESEARCH INSTITUTE
  • 1998~2005 : THE SCRIPPS RESEARCH INSTITUTE
  • 1993~1998 : THE SCRIPPS RESEARCH INSTITUTE
  • 1989~1993 : THE SCRIPPS RESEARCH INSTITUTE

전문분야

학술지

국제전문학술지

  • Transcription factor NFAT1 controls allergic contact hypersensitivity through regulation of activation induced cell death program., SCIENTIFIC REPORTS, , 6, - (2016)
  • Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine, SCIENCE, , 351, 858-863 (2016)
  • Small intestinal eosinophils regulate Th17 cells by producing IL-1 receptor antagonist, JOURNAL OF EXPERIMENTAL MEDICINE, , 213, 555-567 (2016)
  • Intranasal Introduction of Fc-Fused Interleukin-7 Provides Long-Lasting Prophylaxis against Lethal Influenza Virus Infection, JOURNAL OF VIROLOGY, , 90, 2273-2284 (2016)
  • Human antibody reactivity against xenogeneic N-glycolylneuraminic acid and galactose-α-1,3-galactose antigen., XENOTRANSPLANTATION, , 23, 279-292 (2016)
  • Harnessing the IL-7/IL-7R alpha axis to improve tumor immunotherapy., ONCOIMMUNOLOGY, , 5, - (2016)
  • Affinity for self antigen selects T-reg cells with distinct functional properties., NATURE IMMUNOLOGY, , 17, 1093-1101 (2016)
  • The aged lymphoid tissue environment fails to support naive T cell homeostasis., SCIENTIFIC REPORTS, , 6, - (2016)
  • CD45-mediated control of TCR tuning in naive and memory CD8(+) T cells., NATURE COMMUNICATIONS, , 7, - (2016)
  • Microbiota-Independent Ameliorative Effects of Antibiotics on Spontaneous Th2-Associated Pathology of the Small Intestine, PLOS ONE, , 10, - (2015)
  • Induction of Immune Tolerance to Dietary Antigens, ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, , 850, 93-118 (2015)
  • miR-155 augments CD8(+) T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic gamma(c) cytokines, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 112, 476-481 (2015)
  • Pep19 drives epitope spreading in periodontitis and periodontitis-associated autoimmune diseases., JOURNAL OF PERIODONTAL RESEARCH, , , - (2015)
  • Self-gratification yields not-so-naive T cells, NATURE IMMUNOLOGY, , 15, 217-219 (2014)
  • Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients, NATURE COMMUNICATIONS, , 5, - (2014)
  • Crucial Roles of Interleukin-7 in the Development of T Follicular Helper Cells and in the Induction of Humoral Immunity, JOURNAL OF VIROLOGY, , 88, 8998-9009 (2014)
  • Blowing on embers: commensal microbiota and our immune system, FRONTIERS IN IMMUNOLOGY, , 5, 1-10 (2014)
  • IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R, Blood, , 121, 4484-4492 (2013)
  • CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death, Stem Cell Research & Therapy, , 4, 56-56 (2013)
  • IL-2/anti-IL-2 complex attenuates renal ischemia-reperfusion injury through expansion of regulatory T cells, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, , 24, 1529-1536 (2013)
  • Unique Features of Naive CD8+ T Cell Activation by IL-2, The Journal of Immunology, , 191, 5559-5573 (2013)
  • Interleukin 7, maestro of the immune system., Seminars in Immunology, , 24, 149-150 (2012)
  • IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis, Seminars in Immunology, , 24, 209-217 (2012)
  • Selectively Expanding Subsets of T Cells in Mice by Injection of Interleukin-2/Antibody Complexes: Implications for Transplantation Tolerance, Transplantation Proceedings, , 44, 1032-1034 (2012)
  • TGF-Beta puts the brakes on homeostatic proliferation, Nature Immunology, , 13, 1032-1034 (2012)
  • Generation and characterization of human heme oxygenase-1 transgenic pigs, PLoS One, , 7, 628-630 (2012)
  • Interleukin-2/anti-interleukin-2 monoclonal antibody immune complex suppresses collagen-induced arthritis in mice by fortifying interleukin-2/STAT5 signalling pathways, Immunology, , 137, 305-316 (2012)
  • Systemic human T cell developmental processes in humanized mice cotransplanted with human fetal thymus/liver tissue and hematopoietic stem cells, Transplantation, , 94, 1059-1102 (2012)
  • In vivo accumulation of T cells in response to IL-2/anti-IL-2 mAb complexes is dependent in part on the TNF family ligand 4-1BBL, Immunology and Cell Biology, , 90, 743-747 (2012)
  • Dissecting the Requirements for Maintenance of the CMV-Specific Memory T-Cell Pool, Viral Immunology, , 24, 351-355 (2011)
  • Generation of soluble human tumor necrosis factor-α receptor 1-Fc transgenic pig, Transplantation, , 92, 139-147 (2011)
  • Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells, Nature Immunology, , 131, 478-484 (2011)
  • Is IL-7 from dendritic cells essential for the homeostasis of CD4(+) T cells?, Nature Immunology, , 11, 547-548 (2010)
  • IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25., National Academy of Sciences. Proceedings, , 107, 1271-1276 (2010)
  • T Cell Receptor-Dependent Regulation of Lipid Rafts Controls Naive CD8(+) T Cell Homeostasis, Immunity, , 32, 214-226 (2010)
  • Glimpsing the real CD4+ T cell response, Nature Immunology, , 11, 47-49 (2010)

국내전문학술지

일반학술지

  • Homeostatic proliferation of mature T cells, Methods in Molecular Biology, , 979, 81-106 (2013)

학술회의논문

학회발표

단행본

연구실적

  • (국외RISING STAR)면역체계와 공생세균군체간의 상호조절 기작에 대한 규명, 포항공과대학교 (2011-2012)
  • (국제화사업)면역체계와 공생세균군체간의 상호조절 기작에 대한 규명, 포항공과대학교 (2012-2013)
  • 면역 미생물 공생 연구단 유치기관 지원금(IBS), 포항공과대학교 (2012-2017)
  • 면역 미생물 공생 연구단 참여인력 인건비(IBS), 포항공과대학교 (2012-2013)
  • 2015_IBS유치기관지원금(면역미생물공생연구단)CHARLES SURH, 포항공과대학교 (2015-2017)
  • 2016년_IBS유치기관지원금(면역 미생물공생 연구단), 포항공과대학교 (2016-2016)
  • IBB_CHARLES SURH 연구기술원 인건비 지원(1차년도), 포항공과대학교 (2016-2017)

IP

  • 이준영,Surh Charles D., 항-인간 인터루킨-2 항체 및 이의 용도, 한국, 10-2017-0064815 (2017)